MEDIUM FOR INDUCING DIFFERENTIATION OF STEM CELLS INTO MESODERMAL CELLS AND METHOD FOR PRODUCING MESODERMAL CELLS
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United States of America Patent
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May 6, 2021
app pub date -
Jan 25, 2018
filing date -
Jan 26, 2017
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Abstract
The present invention provides a medium for inducing the differentiation of stem cells into mesodermal cells, the medium comprising a ROCK inhibitor, a bone morphogenetic protein (BMP), a fibroblast growth factor (FGF), and activin. The present invention also provides a method for producing mesodermal cells from stem cells using the medium, and method for producing cardiac progenitor cells or myocardiocytes from stem cells using the medium. The present invention furthermore provides a composition for assisting the induction of differentiation of stem cells into mesodermal cells, the composition comprising a ROCK inhibitor, a BMP, an FGF, and activin. The present invention additionally provides cell groups obtained by the above methods.
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