Methods of producing human RPE cells and pharmaceutical preparations of human RPE cells

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11850261
APP PUB NO 20200113938A1
SERIAL NO

16597419

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Abstract

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The present invention provides improved methods for producing retinal pigmented epithelial (RPE) cells from human embryonic stem cells, human induced pluripotent stem (iPS), human adult stem cells, human hematopoietic stem cells, human fetal stem cells, human mesenchymal stem cells, human postpartum stem cells, human multipotent stem cells, or human embryonic germ cells. The RPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The RPE cells described herein are useful for treating retinal degenerative conditions including retinal detachment and macular degeneration.

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Patent Owner(s)

Patent OwnerAddress
ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE33 LOCKE DRIVE MARLBOROUGH MA 01752

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Holmes, William Worcester, US 28 355
Huertas, Pedro Concord, US 8 121
Lemieux, Linda Hubbardston, US 7 121
Malcuit, Christopher Ware, US 15 467
Vilner, Lucy Johnston, US 7 121

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