NOVEL COMBINATION OF CRIZOTINIB WITH CHLOROQUINE FOR INHIBITION OF DIVERSE LUNG TUMORS
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Feb 18, 2021
app pub date -
Aug 13, 2020
filing date -
Aug 15, 2019
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The presently-disclosed subject matter generally relates to methods for sensitizing chemotherapy resistant tumors using a synergistic drug combination. The presently-disclosed subject matter further relates to methods for sensitizing a drug resistant cancer cell to chemotherapy, comprising: contacting the drug resistant cancer cell with an effective amount of an agent capable of increasing cell surface expression of GRP78 and an agent capable of increasing soluble prostate apoptosis response 4 (Par-4).
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