METHODS AND APPARATUS FOR QUANTIFYING PROTEIN ABUNDANCE IN TISSUES VIA CELL FREE RIBONUCLEIC ACIDS IN LIQUID BIOPSY
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United States of America Patent
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Feb 4, 2021
app pub date -
Sep 25, 2020
filing date -
Mar 28, 2018
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Abstract
Methods, systems and apparatus are provided for quantifying the amount of at least a first cell free RNA (cfRNA) present in a liquid biopsy obtained from an individual subject. The first cfRNA may encode a protein that functions in the clearance of xenobiotic compounds from the body of the subject. Quantification of the amount of the first cfRNA is normalised to the individual and permits the construction of more accurate virtual models that facilitate improved personalised medicine, dosage regimens and clinical trials.
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