METHOD FOR PREPARING CANCER STEMNESS CELL LINE THROUGH METABOLIC STRESS, AND CANCER CELL PREPARED THROUGH SAME
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United States of America Patent
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Dec 3, 2020
app pub date -
Apr 20, 2018
filing date -
Apr 21, 2017
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Abstract
The present disclosure relates to a cancer cell line having a stem cellularity and a method for producing the same, and more specifically, to inducing cancer cells to cancer stem cells by applying metabolic stress. More specifically, the present disclosures relates to the production and establishment of the cancer stem cell by repeating culturing in a glucose-deficient medium. The main features of the cancer stem cell produced by the method are that, in a glucose-deficient environment, the resistance to apoptosis is exhibited high and the resistance to anticancer drugs is highly exhibited high.
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