HYDROGEL PARTICLE AND METHOD FOR PRODUCING SAME, CELL OR CELL STRUCTURE EACH ENCLOSING HYDROGEL PARTICLE THEREIN, METHOD FOR EVALUATING ACTIVITY OF CELL USING HYDROGEL PARTICLE, AND USE OF HYDROGEL PARTICLE AS SUSTAINED RELEASE PREPARATION
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United States of America Patent
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Oct 29, 2020
app pub date -
Nov 5, 2018
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Nov 6, 2017
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Abstract
The present invention addresses the problem of providing: a hydrogel particle which can be taken into a cell by the action of the cell and can control the release of a magnetic particle enclosed therein into the cell so as to retain the magnetic particle in the cell for a long period; a method for producing the hydrogel particle; a cell or a cell structure each enclosing the hydrogel particle therein; and a method for evaluating the activity of a cell using the hydrogel particle. The present invention solves the problem by a hydrogel particle including: a domain which is composed of a first hydrogel; a matrix which encloses the domain and is composed of a second hydrogel having a different crosslinking degree or composition from that of the first hydrogel; and a magnetic particle which is supported by at least the first hydrogel.
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