METHOD FOR PREPARING METHIONINE ANALOGUES

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United States of America Patent

APP PUB NO 20200283387A1
SERIAL NO

16070762

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to a method for preparing a compound (I) or one of the salts thereof, and the uses of said method, R1OOC—C(═X)—CHR2R3(I), wherein X is selected among O; N—R′, wherein R′ is H or a C1-C6 alkyl; and N—OR″ wherein R″ is H, or a C1-C6 alkyl or an alkylaryl; R1 is H or a C1-C6 alkyl group; R2 is H, a C1-C6 alkyl, or an alkylaryl; and R3 is CH2SR4 or CH2SeR4, where R4 is H or a C1-C6 alkyl from a compound (II), or one of the salts thereof, R1OOC—C(═X)—CHR2R5 and R5 is H or COOR6, where R6 is H or a C1-C6 alkyl, said method being carried out in the presence of a compound (III) CH2(Y)(Z). Wherein Y is H; OR7, where R7 is H, a C1-C6 alkyl or an acyl with formula CO—R4; SR4 or SeR4 where R4 matches the preceding definition; or 1 NR8R9, where R8 and R9, identical or different, each or together are a C1-C6 alkyl, or an alkylaryl; Z, identical or different to Y, is OR10 where R10 is H, a C1-C6 alkyl or CO—R4; a cyclic or acyclic N(COR4)(COR4) group; or NR11R12, where R11 and R12, identical or different, each or together are a C1-C6 alkyl or an alkylaryl; wherein Y and Z together are ═O; said method involving an intermediate product (IV) R1OOC—C(═X)—CHR2—CH2Z.

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Patent Owner(s)

Patent OwnerAddress
ADISSEO FRANCE S A S10 PLACE DU GÉNÉRAL DE GAULLE ANTONY PARC 2 ANTONY 92160

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
AIRIAU, Etienne VIENNE, FR 3 7
AUBRY, Sylvain CALAIS, FR 2 1
HENRYON, Vivien LYON, FR 8 12
HUET, Robert PARIS, FR 13 14
MONBRUN, Jérôme CHUZELLES, FR 2 0
REY, Patrick LYON, FR 13 14

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