ACTIVITY-DEPENDENT GENE PAIRS AS THERAPEUTIC TARGETS AND METHODS AND DEVICES TO IDENTIFY THE SAME

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United States of America Patent

APP PUB NO 20200263250A1
SERIAL NO

16826010

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Abstract

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Activity-dependent gene pairs as therapeutic targets and methods and devices to identify the same are provided. The methods and devices allow transcriptome-wide analysis of regulatory long non-coding RNAs (lncRNAs), matched with differentially expressed protein-coding genes (mRNAs) and/or with other lncRNAs. The described methods and devices allow analysis of these activity-dependent gene pairs as therapeutic targets in a number of clinical conditions associated with altered electrical brain activity, including epilepsy.

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Patent Owner(s)

Patent OwnerAddress
WAYNE STATE UNIVERSITY4032 F/AB 656 W KIRBY DETROIT MI 48202

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lipovich, Leonard Detroit, US 2 0
Loeb, Jeffrey A Beverly Hills, US 8 12

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