MODIFIED TEMPLATE-INDEPENDENT DNA POLYMERASE
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United States of America Patent
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Aug 20, 2020
app pub date -
May 22, 2018
filing date -
May 22, 2017
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Abstract
Described herein are genetically engineered template-independent DNA polymerases, specifically terminal deoxynucleotidyl transferases, and methods of using these polymerases to control DNA synthesis by adding a single nucleotide (mononucleotide) at a time to the 3′ end of a growing single-stranded DNA polynucleotide.
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