THYMIDINE KINASE GENE
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United States of America Patent
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Issued Date -
Jun 11, 2020
app pub date -
Feb 21, 2020
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Mar 14, 2013
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Abstract
Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
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