NANOSTRUCTURED TITANIUM-BASED COMPOSITIONS AND METHODS TO FABRICATE THE SAME
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United States of America Patent
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May 14, 2020
app pub date -
Oct 3, 2019
filing date -
Apr 7, 2017
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Abstract
Provided herein are methods for the controlled, independent modification of the surface of titanium-based materials and compositions generated thereby. The methods allow for the alteration of multiple surface characteristics including generation of precise nanostructures, morphology, crystallography and chemical composition for increased biocompatibility, for example, osseointegration, osseoconduction, cell adhesion, cell proliferation, mechanical properties (e.g. elasticity, modulus, surface texture, porosity), hydrophobicity, hydrophilicity, steric hindrance, anti-inflammatory properties and/or anti-bacterial properties.
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