RECOMBINANT MICROORGANISM, METHOD OF PRODUCING PYRIDOXAMINE OR SALT THEREOF USING RECOMBINANT MICROORGANISM, AND METHOD OF PRODUCING PYRIDOXAL OR SALT THEREOF USING RECOMBINANT MICROORGANISM
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United States of America Patent
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Apr 23, 2020
app pub date -
May 11, 2018
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May 12, 2017
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A recombinant microorganism includes a gene encoding a pyridoxine dehydrogenase, a gene encoding a pyridoxamine synthetase having an enzymatic activity of synthesizing pyridoxamine from pyridoxal, and a gene encoding an amino acid regeneration enzyme having an enzymatic activity of regenerating an amino acid consumed by the pyridoxamine synthetase, in which at least two of the gene encoding the pyridoxine dehydrogenase, the gene encoding the pyridoxamine synthetase, or the gene encoding the amino acid regeneration enzyme, are introduced from outside of a bacterial cell, or are endogenous to the bacterial cell and have an enhanced expression. In addition, a recombinant microorganism into which a gene encoding a pyridoxine dehydrogenase is introduced is provided.
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