ELECTROPHORESIS METHOD WITH VARYING ELECTRICAL FIELD
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United States of America Patent
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Apr 16, 2020
app pub date -
Jun 13, 2018
filing date -
Jun 13, 2017
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Abstract
The invention provides an electrophoresis method for detecting an analyte in a sample, the method comprising providing the sample and an agent that specifically binds the analyte, combined in a fluid medium in a separation channel; applying an electric field along the separation channel, the electric field having a field profile, and thereby causing bound and unbound analyte and/or agent to move relative to the fluid; varying the applied electric field so as to adjust the field profile relative to the separation channel, thereby causing the bound analyte and the unbound analyte to concentrate at locations apart from one another in the fluid under the combined influences of an electric force due to the electric field and a hydrodynamic force due to the fluid.
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