METHOD FOR DETERMINING SENSITIVITY TO A CDK4/6 INHIBITOR

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20190345558A1
SERIAL NO

16092177

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention relates to a method for determining sensitivity to a cyclin-dependent kinase 4/6 (CDK4/6) inhibitor in a human subject having breast cancer, the method comprising determining in a sample from the subject the level of expression of 11 genes as defined in the claims. The present invention further provides kits of parts, nucleic acid arrays, and uses thereof for determining sensitivity to a CDK4/6 inhibitor in a human subject having breast cancer. The present invention also relates to methods of treating a human subject having breast cancer, comprising administering a therapeutically effective amount of the CDK4/6 inhibitor to the subject.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
UNIVERSITE LIBRE DE BRUXELLESBRUXELLES

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
COULONVAL, Katia Enghien, BE 2 7
GOMES, PITA Jaime Miguel Etterbeek, BE 1 4
IGNATIADIS, Michail Bruxelles, BE 1 4
PATERNOT, Sabine Hoves, BE 2 7
RASPÉ, Eric Mouscron, BE 1 4
ROGER, Pierre Philippe Bruxelles, BE 1 4
ROTHÉ, Françoise Bruxelles, BE 1 4
SOTIRIOU, Christos Bruxelles, BE 9 27

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation