MULTIMODAL ASSAY FOR DETECTING NUCLEIC ACID ABERRATIONS
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United States of America Patent
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Oct 10, 2019
app pub date -
Nov 16, 2017
filing date -
Nov 16, 2016
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The invention provides methods for determining whether a subject is predisposed to the disease or condition, or for diagnosing a disease or condition, or for detecting the state of a disease or condition, by detecting nucleic acid fragment size patterns, copy number variations, mutational landscape, genomic instability, methylation status, and combinations thereof in a subject. The invention further provides methods for selecting nucleic acid molecules for use in the methods of the invention.
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