Compositions, devices and methods for the control in vitro of chemical microambient in cell cultures

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11920153
APP PUB NO 20190300846A1
SERIAL NO

16339164

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Abstract

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The present invention relates to compositions comprising a polymeric matrix or a gel containing functional enzymes capable of re-creating under culture conditions the cell microenvironment existing in vivo. The present invention also relates to devices for cell cultures comprising such compositions, in particular hydrogel and the use thereof to control the chemical microenvironment of a cell culture or mimic physiological or pathological conditions of the in vivo cells. The compositions and the devices described herein could be also used in vitro for evaluating the therapeutic effect of a compound on a determined cell line or on primary cells.

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Patent Owner(s)

Patent OwnerAddress
ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA40126 BOLOGNA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Becconi, Maila Nuoro, IT 2 0
Castellani, Gastone Bologna, IT 2 0
Conte, Maria Marzabotto, IT 2 0
Fraboni, Beatrice Bologna, IT 12 57
Franceschi, Claudio Bologna, IT 3 2
Rapino, Stefania Bologna, IT 2 0
Salvatore, Daniela Lanciano, IT 2 0
Salvioli, Stefano Bologna, IT 2 0
Zerbetto, Francesco Bologna, IT 4 0
Zironi, Isabella Caselecchio di Reno, IT 2 0

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