Elimination of proliferating cells from stem cell-derived grafts

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11542524
APP PUB NO 20190160113A1
SERIAL NO

16204320

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Provided herein are methods and compositions for a suicide gene approach comprising an expression vector comprising a cell cycle-dependent promoter driving the expression of a suicide gene. Also provided herein are methods to render proliferative cells sensitive to a prodrug after transplantation but avoids expression of the suicide gene in post-mitotic cells, such as neurons.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
RESEARCH DEVELOPMENT FOUNDATION402 NORTH DIVISION STREET CARSON CITY NV 89703

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dubois-Dauphin, Michel Geneva, CH 4 0
Krause, Karl-Heinz Geneva, CH 44 229
Tieng, Caulet Vannary Geneva, CH 4 0

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
3.5 Year Payment $1600.00 $800.00 $400.00 Jul 3, 2026
7.5 Year Payment $3600.00 $1800.00 $900.00 Jul 3, 2030
11.5 Year Payment $7400.00 $3700.00 $1850.00 Jul 3, 2034
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00