Means and methods for generating complex glycans derived from fungal engineered hosts
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United States of America Patent
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Mar 9, 2021
Grant Date -
May 16, 2019
app pub date -
May 3, 2017
filing date -
May 3, 2016
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Abstract
The present application relates to the field of glyco-engineering, more specifically to glycosylation-engineered fungal cells, more specifically glycosylation-engineered yeast cells, optimized to produce highly homogenous forms of complex N-glycans on recombinant proteins. The invention specifically relates to methods to obtain pharmaceutical compositions comprising recombinant glycoproteins which have homogenous forms of complex N-glycans. In addition, the invention relates to novel pharmaceutical compositions which result from the methods of the invention.
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