Ketoreductase polypeptides for the reduction of acetophenones
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United States of America Patent
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Feb 23, 2021
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May 16, 2019
app pub date -
Jan 22, 2019
filing date -
Sep 13, 2007
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Abstract
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.
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