SUBSTITUTED 2, 4-DIAMINO-QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES

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United States of America Patent

APP PUB NO 20190144437A1
SERIAL NO

16098546

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This application discloses compounds according to generic Formula I: wherein all variables are defined as described herein which exhibit strong inhibition effects on various cancer cell lines. The compounds disclosed herein are useful for the treatment of proliferative diseases, including neoplastic diseases such as cancer and non-neoplastic disorders such as rheumatoid arthritis. Also disclosed are pharmaceutical compositions containing compounds of Formula I and at least one carrier, diluent or excipient and optionally one or more additional therapeutically active agents, including anticancer agents. This application also discloses methods for treating a proliferative disease, including neoplastic diseases such as cancer and non-neoplastic disorders such as rheumatoid arthritis.

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Patent Owner(s)

Patent OwnerAddress
GENOSCIENCE PHARMA13006 MARSEILLE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BASSISSI, Firas Marseille, FR 6 1
BERET, Antoine Marseille, FR 4 1
BRUN, Sonia Aix-En-Provence, FR 4 0
COURCAMBECK, Jérôme Marseille, FR 4 0
HALFON, Philippe Marseille, FR 12 29

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