METHOD FOR ENHANCING DELIVERY OF THERAPEUTIC DRUGS TO TREATMENT SITES
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United States of America Patent
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Issued Date -
May 9, 2019
app pub date -
Jan 2, 2019
filing date -
Jan 2, 2019
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Abstract
Disclosed herein is a method for enhancing uptake of magnetic nanoparticles (MNPs) having a therapeutic agent associated therein to a target site (e.g., a tumor), thereby resulting in elevated level of therapeutic agents being accumulated in the target site. The method comprises concurrently administering a sufficient amount of a polyphenolic compound and MNPs to the target site. Also disclosed herein is a method for treating a cancer in a subject. The method comprises concurrently administering an effective amount of the polyphenolic compound and MNPs to the subject, so as to ameliorate or alleviate symptoms associated with the cancer.
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