METHOD OF MAKING CASEIN PARTICLES ENCAPSULATING THERAPEUTICALLY ACTIVE AGENTS AND USES THEREOF
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United States of America Patent
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Issued Date -
Mar 28, 2019
app pub date -
Jun 8, 2018
filing date -
Jun 8, 2018
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Abstract
Casein particles, such as micelles or clusters thereof having encapsulated therein hydrophobic and/or water insoluble therapeutically active agents such as hydrophobic chemotherapeutic agents, which are otherwise administered parenterally, are disclosed. Pharmaceutical compositions containing the casein particles and uses thereof in the treatment of cancer and other conditions treatable by the encapsulated therapeutically active agent are also disclosed. Further disclosed are processes of preparing the casein particles. The disclosed casein particles are useful for orally delivering the therapeutically active encapsulated therein and can further be used for controllably releasing the agents in the gastrointestinal tract.
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