Functionalized nanoparticles for enhanced affinity precipitation of proteins

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United States of America Patent

PATENT NO 11149060
APP PUB NO 20190048039A1
SERIAL NO

16076418

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Abstract

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The present invention provides a nanoparticle capable of binding specifically to a target protein in a solution and precipitating with the target protein out of the solution upon addition of the target protein to the solution. The precipitation may be reversed release the target protein from the nanoparticle, which may be reused for precipitating the target protein. Also provided are a method for purifying a target protein by affinity precipitation using the nanoparticle without chromatography and a method for preparing the nanoparticle.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF DELAWARE1 INNOVATION WAY DELAWARE TECHNOLOGY PARK BUILDING 1 SUITE 500 NEWARK DE 19711

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Wilfred Hockessin, US 6 60
Swartz, Andrew Newark, US 12 54

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