Double-stranded oligonucleotide molecules targeting p53 and methods of use thereof

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United States of America Patent

PATENT NO 10781449
APP PUB NO 20190040385A1
SERIAL NO

15942587

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Abstract

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The present application relates to nucleic acid compounds, compositions comprising same and methods of use thereof for treatment of various diseases, disorders and conditions. The compounds are preferably chemically synthesized and modified double-stranded nucleic acid molecules which down regulate expression of a p53 gene.

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Patent Owner(s)

Patent OwnerAddress
QUARK PHARMACEUTICALS INC6501 DUMBARTON CIRCLE FREMONT CA 94555

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Avkin-Nachum, Sharon Nes Zionna, IL 30 149
Feinstein, Elena Rehovot, IL 146 1572
Kalinski, Hagar Rishon-le-Zion, IL 47 370
Mett, Igor Rehovot, IL 73 671

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