SINGLE VARIABLE DOMAIN ANTIBODIES AGAINST OX40L, CONSTRUCTS AND THERAPEUTIC USE

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United States of America Patent

APP PUB NO 20180171019A1
SERIAL NO

15795442

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Abstract

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The present invention relates to immunoglobulin single variable domain sequences that are directed against (as defined herein) OX40L, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such immunoglobulin single variable domain sequences. In particular these immunoglobulin single variable domain sequences can block binding of OX40L to OX40.

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Patent Owner(s)

  • ABLYNX N.V.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cornells, Sigrid Sint Martens Latem, BE 1 0
Staelens, Stephanie Wevelgem, BE 41 286
VERDONCK, FRANK Sint-Gillis-Waas, BE 3 46

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