Chimeric polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same

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United States of America Patent

PATENT NO 10730925
APP PUB NO 20180327476A1
SERIAL NO

16045848

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Abstract

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A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising:

    (i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and(ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.

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Patent Owner(s)

Patent OwnerAddress
PROTALIX LTD2010000 CARMIEL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ariel, Tami Manof, IL 6 11
Gingis-Velitski, Svetlana Kiryat-Motzkin, IL 6 11
Hanania, Uri Carmiel, IL 14 30
Kizhner, Tali Atzmon-Segev, IL 16 58
Shaaltiel, Yoseph Timrat, IL 43 445

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