NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACID COMPLEXES

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United States of America Patent

APP PUB NO 20180311176A1
SERIAL NO

15771321

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Aspects of the disclosure relate to particle formulations, e.g., nanoparticle formulations, methods of making particle formulations, and methods for delivery of oligonucleotides and/or synthetic RNA, e.g., for increasing gene expression in a targeted manner. In some embodiments, compositions and methods are provided that are useful for posttranscriptionally altering protein and/or RNA levels in a targeted manner. Aspects of the disclosure described herein provide compositions and methods that are useful for protecting RNAs from degradation (e.g., exonuclease mediated degradation).

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Patent Owner(s)

Patent OwnerAddress
TRANSLATE BIO MA INC29 HARTWELL AVENUE LEXINGTON MA 02421

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bhat, Balkrishen Carlsbad, US 173 7460
Ozsolak, Fatih Boston, US 22 199

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