SYNTHESIS OF ESTETROL VIA ESTRONE DERIVED STEROIDS

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United States of America Patent

APP PUB NO 20180265540A1
SERIAL NO

15982284

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Abstract

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A process is provided for the making of estetrol starting from a 3-A-oxy-estra-1,3,5(10),15-tetraen-17-one, wherein A is an C1-C5 alkyl group, preferably a methyl group, or a C7-C12 benzylic group, preferably a benzyl group. This process is particularly suitable to industry.

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Patent Owner(s)

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DONESTA BIOSCIENCE B V3701 CH ZEIST

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
KOCH, Thomas Groningen, NL 137 823
VERHAAR, Mark Theodoor Groningen, NL 4 39
WARMERDAM, Erwin Gerardus Jacobus Weert, NL 3 39

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