Intelligent continuous manufacturing method via liquid cooling of dripping pills

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United States of America Patent

PATENT NO 10813840
APP PUB NO 20180256450A1
SERIAL NO

15760367

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Abstract

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An intelligent continuous manufacturing method via liquid cooling of dripping pills comprises the following steps: (1) feeding: weighing and transferring multiple materials respectively; (2) material combining: performing staged heating on the materials transferred in step (1), and mixing the same to obtain a material mixture, wherein an RSD of an effective ingredient in the material mixture ≤5%; (3) homogenizing: pressurizing the material mixture obtained in step (2), and increasing the temperature, so as to obtain a homogenized material having the RSD of the effective ingredient in the material mixture ≤5%; (4) dripping: performing vibration dripping on the homogenized material obtained in step (3) to obtain dripping pills, delivering the dripping pills into a cooling liquid to be cooled and then transferred; and (5) de-oiling: removing the cooling liquid on surfaces of the dripping pills obtained in step (4) via tilting centrifugation. The manufacturing method not only shortens the manufacturing process, but also ensures the dripping pill product to be more stable and homogeneous. In addition, high-speed centrifugation is used to reasonably de-oil the dripping pills to prevent contamination of the dripping pills and improve the circulation utilization rate of the cooling liquid.

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Patent Owner(s)

Patent OwnerAddress
TASLY PHARMACEUTICAL GROUP CO LTDTIANJIN 300410

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cai, Xuefei Tianjin, CN 32 236
Rong, Changsheng Tianjin, CN 4 4
Sun, Xiaobing Tianjin, CN 31 289
Wang, Liang Tianjin, CN 656 6142
Yan, Kaijing Tianjin, CN 18 20

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