IMMUNOLOGICAL TEST METHOD AND IMMUNOLOGICAL TEST KIT
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United States of America Patent
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Aug 30, 2018
app pub date -
Aug 19, 2016
filing date -
Aug 21, 2015
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Abstract
It was found that when measuring HMGB1 in samples using antibodies that bind to both HMGB2 and HMGB1, the reaction between HMGB2 and HMGB1 antibodies can be suppressed by coexisting HMGB2 absorbents (HMGB2 antibodies and/or HMGB2-derived peptides that inhibit the binding between HMGB2 and HMGB1 antibodies). More specifically, it was revealed that HMGB1 alone in samples can be measured or detected by contacting the samples with HMGB1 antibodies in the presence of HMGB2 absorbents.
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