ANTI-DENGUE VIRUS ANTIBODIES AND USES THEREOF

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United States of America Patent

APP PUB NO 20180246101A1
SERIAL NO

15833110

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Abstract

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The present invention provides, among other things, antibody agents (e.g., antibodies, and/or antigen-binding fragments thereof) that bind to DV epitopes, as well as compositions containing them and methods of designing, providing, formulating, using, identifying and/or characterizing them. In some embodiments, provided antibody agents show significant binding to a plurality of DV serotypes. In some embodiments, provided antibody agents show significant binding to all four DV serotypes. Such antibody agents are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of DV.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139-4307

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Robinson, Luke Nathaniel Quincy, US 4 352
Sasisekharan, Ram Lexington, US 136 3562
Tharakaraman, Kannan Woburn, US 22 470

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