METHODS AND MEANS FOR DYSPLASIA ANALYSIS
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Jul 1, 2016
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Jul 24, 2015
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Some embodiments are directed to a method of aiding the diagnosis of dysplasia in a subject that includes providing a sample from the oesophagus of the subject; assaying the sample for expression of each of the genes shown in the ‘40 genes’ column of Table 1; normalising the expression levels of the genes in step (b) to expression levels of reference gene(s) from a non-dysplastic sample; and determining from the normalised expression levels of step (c) a gene signature score for the sample, wherein a gene signature score greater than a reference threshold indicates presence of dysplasia in the subject. Some embodiments also relate to devices, compositions, primer sets, arrays, methods of treatment and computer programs.
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