Methods for modulating expression of C9ORF72 antisense transcript

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United States of America Patent

PATENT NO 11162096
APP PUB NO 20180142240A1
SERIAL NO

15848389

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Abstract

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Disclosed herein are compositions and methods for reducing expression of C9ORF72 antisense transcript in an animal with C9ORF72 antisense transcript specific inhibitors. Such methods are useful to treat, prevent, or ameliorate neurodegenerative diseases in an individual in need thereof. Such C9ORF72 antisense transcript specific inhibitors include antisense compounds.

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Patent Owner(s)

Patent OwnerAddress
IONIS PHARMACEUTICALS INCCARLSBAD CA 92010

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baughn, Michael W La Jolla, US 3 62
Bennett, C Frank San Diego, US 412 7677
Cleveland, Don W Del Mar, US 27 262
Lagier-Tourenne, Clotilde Winchester, US 3 62
Ravits, John M La Jolla, US 3 62
Rigo, Frank Carlsbad, US 107 661

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