Methods of preparing ophthalmic formulations and uses of same
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United States of America Patent
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Jul 16, 2019
Grant Date -
May 10, 2018
app pub date -
Jan 8, 2018
filing date -
Oct 31, 2013
priority date (Note) -
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Abstract
The present invention relates to a process for preparing an ointment comprising subjecting a mixture of a fluorescent molecular rotor compound, mineral oil, and grinding media to ball milling agitation and combining this mixture with a hydrophobic vehicle for an ointment. The invention also relates to an ophthalmic formulation comprising a pharmaceutically acceptable carrier and a compound of the following structural Formula (I), or a pharmaceutically acceptable salt thereof:
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