Chimeric polypeptides

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United States of America Patent

PATENT NO 10648045
APP PUB NO 20180073089A1
SERIAL NO

15562085

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Abstract

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Chimeric clostridial neurotoxins in which the activation loop has been replaced by an activation loop from a different subtype within the same serotype. Methods of producing, activating, and using such neurotoxins. Compositions comprising such neurotoxins. Polynucleotides, vectors and cells for expressing such neurotoxins.

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Patent Owner(s)

Patent OwnerAddress
IPSEN BIOPHARM LIMITEDUNIT 9 ASH ROAD WREXHAM INDUSTRIAL ESTATE WREXHAM LL13 9UF

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burgin, David Abingdon, GB 2 4
Hackett, Stephen Gavin Abingdon, GB 1 6
Kwan, Daniel Abingdon, GB 2 6

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