High-efficiency transfection of biological cells using sonoporation
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United States of America Patent
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Sep 29, 2020
Grant Date -
Mar 15, 2018
app pub date -
Sep 15, 2017
filing date -
Sep 15, 2016
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Abstract
A method is provided for achieving transfection of host cells using sonoporation. An acoustic radiation generator is positioned in acoustic coupling relationship with respect to a reservoir containing host cells to be transfected, exogenous material to be incorporated into the host cells, and a cell-compatible fluid medium. The acoustic radiation generator is activated to generate acoustic radiation and direct the acoustic radiation into the reservoir in a manner effective to enable transfection of the host cells with the exogenous material.
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