Functional cure of retroviral infection

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United States of America Patent

PATENT NO 10806734
APP PUB NO 20180071288A1
SERIAL NO

15559077

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Abstract

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The application relates to methods of curing retroviral infections, i.e. ensuring remission of retroviral infections, more particularly HIV infections, by administering a compound which is capable of binding to the LEDGF/p75 binding pocket of HIV-integrase and inhibiting LEDGF/p75-IN protein-protein interaction. The application further relates to the use of LEDGINs in retroviral gene therapy.

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Patent Owner(s)

Patent OwnerAddress
KATHOLIEKE UNIVERSITEIT LEUVEN KU LEUVEN R&DWAAISTRAAT 6 - BOX 5105 LEUVEN 3000

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Christ, Frauke Heverlee, BE 9 36
Debyser, Zeger Heverlee, BE 16 74
Gijsbers, Rik Blanden, BE 2 0
Vranckx, Lenard Hulshout, BE 2 0

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