EML4-ALK FUSION GENE

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United States of America Patent

SERIAL NO

15810918

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Abstract

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The present inventors found that a fusion gene present in some cancer patients is an oncogene. The present invention relates to a polypeptide as a novel fusion protein, a polynucleotide encoding the polypeptide, a vector comprising the polynucleotide, a transformed cell comprising the vector, a method for detecting the fusion protein or polynucleotide, a method for screening a therapeutic agent for cancer, and a method for treating cancer that is shown to be positive for the fusion gene. Further, the present invention relates kit, primer set, and probe useful in the detection of cancer that is shown to be positive for the fusion gene

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Patent Owner(s)

Patent OwnerAddress
ASTELLAS PHARMA INC5-1 NIHONBASHI-HONCHO 2-CHOME CHUO-KU TOKYO 103-8411 JAPAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Furutani, Takashi Tokyo, JP 38 245
Kuromitsu, Sadao Tokyo, JP 17 322
MANO, HIROYUKI Tokyo, JP 86 1020
Shindo, Nobuaki Tokyo, JP 22 237
Soga, Takatoshi Tokyo, JP 17 252

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