System and method for biphasic transdermal iontophoretic therapeutic agents

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United States of America Patent

PATENT NO 10780266
APP PUB NO 20180064934A1
SERIAL NO

15679924

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Abstract

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Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion.

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Patent Owner(s)

Patent OwnerAddress
INCUBE LABS LLC2051 RINGWOOD AVENUE SAN JOSE CA 95131

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arastu, Huma San Jose, US 3 51
Harris, Joel Mountain View, US 34 313
Hashim, Mir Fremont, US 48 1459
Imran, Mir Los Altos, US 274 12508
Korupolu, Radhika San Jose, US 27 488
Mangogna, Andrew San Jose, US 3 51
McLaughlin, Glen San Carlos, US 36 1023
Ong, Chang San Jose, US 3 51
Patel, Sanjay San Jose, US 151 3472
Vaidyanathan, Rekha San Jose, US 4 59
Wang, Lu San Jose, US 460 6920
Williams, Timothy San Jose, US 83 3184

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