USE OF BISPHOSPHONATES AS HIV/AIDS ADJUNCTIVE TREATMENT

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United States of America Patent

SERIAL NO

15783170

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Abstract

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The present invention relates to use of bisphosphonate formulations for the treatment and management of HIV/AIDS. The method of the invention comprises administering a formulation comprising an effective amount of a bisphosphonate that specifically inhibits the activity and/or decreases the number of monocytes and/or macrophages, thereby reducing or eliminating HIV reservoirs. The invention also provides a method of complementing an HIV antiviral therapy, such as the highly active antiretroviral therapy (HAART), with a bisphosphonate formulation to improve clinical outcome.

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Patent Owner(s)

Patent OwnerAddress
ZULI HOLDINGS LTD61581 TEL-AVIV

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
GOLOMB, Gershon Efrat, IL 30 412
RICHTER, Yoram Ramat Hasharon, IL 41 1466
SACHA, Jonah B Beaverton, US 4 0

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