EXTENDING ASSEMBLY CONTIGS BY ANALYZING LOCAL ASSEMBLY SUB-GRAPH TOPOLOGY AND CONNECTIONS
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Aug 21, 2017
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Aug 23, 2016
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Aspects of the present disclosure provide methods, systems, and computer program products for generating one or more extended contigs. Aspects of the exemplary embodiment include receiving input contigs for a genome; generating local assembly subgraphs including the ends of each contig; identifying subgraphs that unambiguously connect two contigs; and generating an extended contig in which the orientation and order of at least two contigs is determined. Extended contigs can include any number of linearly ordered and linked contigs.
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