PERCUTANEOUS MODIFICATION OF VASCULAR EXTRACELLULAR MATRIX TO PREVENT AND TREAT VASCULAR RESTENOSIS
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Mar 17, 2016
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Mar 18, 2015
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Aspects of disclosed embodiments relate to systems, devices and methods for treating and preventing restenosis by cross-linking collagen fibrils of the vessel wall at the intervention site. The devices described are drug-eluting devices comprising: an expandable member or a balloon; a cross-linking agent; and a photoactivating light source. Upon the inflation of the expandable member or the balloon the cross linking agent is released and photoactivated in a therapeutically effective amount for cross-linking collagen fibrils.
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