METHOD AND KIT FOR EXAMINING COMPLEMENT SYSTEM
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United States of America Patent
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Aug 9, 2017
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Aug 16, 2016
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Abstract
A method for examining a complement system of a subject, including: a reaction step of letting a scavenger receptor or a functional equivalent thereof, a pentraxin family protein or a functional equivalent thereof and a blood sample collected from the subject coexist in vitro; and a detection step of detecting complement activation amplifying reaction and/or complement activation late-phase reaction induced by interaction between the scavenger receptor or the functional equivalent thereof and the pentraxin family protein or the functional equivalent thereof from a reactant after the reaction step. Also provided are a kit for examining a complement system, and a method for testing a test substance for the ability to activate or suppress a complement system.
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