ANTIBODY HIGHLY SPECIFICALLY RECOGNIZING TURN STRUCTURE AT 22- AND 23-POSITIONS IN AMYLOID BETA

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United States of America Patent

APP PUB NO 20180051071A1
SERIAL NO

15533852

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided is an antibody or an immunologically reactive fragment thereof which targets exclusively an Aβ having a specific turn structure of Aβ (a toxic conformer of Aβ). Also provided are a medicinal composition comprising, as an active ingredient, an antibody that specifically recognizes a toxic conformer of Aβ, a kit for assaying a toxic conformer of Aβ, a diagnostic agent for Alzheimer's disease, etc.

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Patent Owner(s)

Patent OwnerAddress
KYOTO UNIVERSITY36-1 YOSHIDA-HONMACHI SAKYO-KU KYOTO-SHI KYOTO 606-8501
IMMUNO-BIOLOGICAL LABORATORIES CO LTD1091-1 NAKA AZA-HIGASHIDA FUJIOKA-SHI GUNMA 375-0005
NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITYCHIBA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Irie, Kazuhiro Kyoto-shi, Kyoto, JP 14 137
Izuo, Naotaka Chiba-shi, Chiba, JP 1 0
Murakami, Kazuma Kyoto-shi, Kyoto, JP 3 2
Seito, Tsutomu Fujioka-shi, Gunma, JP 8 12
Shimizu, Takahiko Chiba-shi, Chiba, JP 25 95

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