Anti-PAD4 antibody

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11447569
APP PUB NO 20180044434A1
SERIAL NO

15555808

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Abstract

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Provided are anti-PAD4 antibodies having excellent properties and an excellent method for treatment of RA. Used are anti-PAD4 antibodies that specifically bind to an epitope containing positions 345, 347, and 348 of PAD4. These anti-PAD4 antibodies may inhibit the citrullination activity of PAD4. In addition, these anti-PAD4 antibodies may have a KD (M) of 9.0×10−9 or less. Optionally, the anti-PAD4 antibody and a TNFα inhibitor are used in combination.

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Patent Owner(s)

Patent OwnerAddress
PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY22-2 SETO KANAZAWA-KU YOKOHAMA-SHI KANAGAWA 2360027
PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY1 AZA-KAWASUMI MIZUHO-CHO MIZUHO-KU NAGOYA-SHI AICHI 4678601
PHARMA FOODS INTERNATIONAL CO LTD1-49 GORYO-OHARA NISHIKYO-KU KYOTO-SHI KYOTO 6158245

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kanazawa, Satoshi Nagoya, JP 20 192
Saito, Kenji Kyoto, JP 306 2143
Sato, Mamoru Yokohama, JP 68 946
Shoya, Yuji Kyoto, JP 8 10
Toyoura, Masayoshi Kyoto, JP 8 10
Yamada, Michiyuki Yokohama, JP 3 5
Yamazaki, Chihiro Kyoto, JP 5 7

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