Combination therapy with a hyaluronan-degrading enzyme and an immune checkpoint inhibitor

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United States of America Patent

PATENT NO 11414489
APP PUB NO 20170218069A1
SERIAL NO

15444151

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Abstract

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Provided are methods of treatments with combinations or compositions containing a soluble hyaluronidase, such as a polymer-modified hyaluronidase, and an immune checkpoint inhibitor treating cancers, including solid and non-solid tumors. The combinations and compositions also are provided.

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Patent Owner(s)

Patent OwnerAddress
HALOZYME INC11388 SORRENTO VALLEY ROAD SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rosengren, Sanna Encinitas, US 4 13
Shepard, H Michael Springfield, US 88 2797
Thompson, Curtis B San Diego, US 9 289

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