4-substituted benzoxaborole compounds and uses thereof
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United States of America Patent
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Sep 15, 2020
Grant Date -
Feb 15, 2018
app pub date -
Feb 12, 2016
filing date -
Feb 12, 2015
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Abstract
Substituted benzoxaboroles whose structure comprises Formula (III), wherein R3 is selected from —CH3, —CH2CH3, —CH2═CH2, —CH2CH2CH3, —CH(CH3)2, —CH2CH2═CH2, and cyclopropyl, R1 and R2 are each independently selected from H, —CH3, —CH2CH3, —CH2CH2CH3, and —CH(CH3)2; compositions containing such compounds, their use in therapy, including their use as anti-mycobacterial agents, for example in the treatment of a mycobacterial infection in a mammal, and methods for the preparation of such compounds, are provided.
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