1,2,4-Oxadiazole and thiadiazole compounds as immunomodulators

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United States of America Patent

PATENT NO 10781189
APP PUB NO 20180044303A1
SERIAL NO

15556800

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Abstract

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The present invention relates to 1,2,4-oxadiazole compounds of formula (I) and their use to inhibit the programmed cell death 1 (PD-1) signaling pathway and/or for treatment of disorders by inhibiting an immunosuppressive signal induced by PD-1, PD-L1 or PD-L2.

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Patent Owner(s)

  • AURIGENE DISCOVERY TECHNOLOGIES LIMITED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Naremaddepalli, Seetharamaiah Setty Sudarshan Bangalore, IN 28 248
Ramachandra, Muralidhara Bangalore, IN 52 528
Sasikumar, Pottayil Govindan Nair Bangalore, IN 31 276

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