Cyclosporine formulations for use in the prevention or treatment of pulmonary chronic graft rejection

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United States of America Patent

PATENT NO 10857198
APP PUB NO 20180042988A1
SERIAL NO

15558102

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Abstract

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The invention relates to cyclosporine formulations for use in the prevention or treatment of pulmonary chronic graft rejection. In particular, the invention provides a cyclosporine liquid formulation for use as an aerosol for inhalation in a method of preventing or treating pulmonarychronic graft rejection in single lung transplanted patients. The formulation is preferably administered once or twice daily. The formulation may be aerosolized with a nebulizer that comprises features for monitoring the time, date and duration of inhalation by the patient, in order to monitor patient adherence. The formulation according to the invention may be combined with standard immunosuppressants and corticosteroids.

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Patent Owner(s)

Patent OwnerAddress
BREATH THERAPEUTICS GMBH80639 MÜNCHEN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Denk, Oliver Münsing, DE 14 9
Knoch, Martin Garmisch-Partenkirchen, DE 39 1783

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