Bromodomain inhibitor

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 10702517
APP PUB NO 20180042914A1
SERIAL NO

15788741

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Abstract

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Described herein is the bromodomain inhibitor 4-[2-(cyclopropylmethoxy)-5-methylsulfonylphenyl]-2-methylisoquinolin-1-one, including crystalline forms, amorphous forms, solvates, and hydrates thereof, as well as pharmaceutical compositions that include this bromodomain inhibitor. In some embodiments, the pharmaceutical composition comprises 4-[2-(cyclopropylmethoxy)-5-methylsulfonylphenyl]-2-methylisoquinolin-1-one that has been processed by micronization or spray dried dispersion. In some embodiments, the pharmaceutical composition further comprises at least one polymer. In some embodiments, the pharmaceutical composition comprises a solid polymer matrix comprising 4-[2-(cyclopropylmethoxy)-5-methylsulfonylphenyl]-2-methylisoquinolin-1-one and at least one polymer. Pharmaceutical compositions comprising 4-[2-(cyclopropylmethoxy)-5-methylsulfonylphenyl]-2-methylisoquinolin-1-one are useful for the treatment of cancer or neoplastic disease.

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Patent Owner(s)

Patent OwnerAddress
CELGENE QUANTICEL RESEARCH INC10300 CAMPUS POINT DRIVE SUITE 100 SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Betancort, Juan Manuel San Diego, US 22 187
Stafford, Jeffrey Alan San Diego, US 99 548
Stansfield, Ryan San Diego, US 4 8
Veal, James Marvin Apex, US 109 976

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